OLDER Structures (These will conform to the new format in time)


Formyl-CoA Transferase (FRC) 1P5H, 1P5R, 1T3Z, 1VGR, 1VGQ, 2VGM, 2VGK, 2VGP  at RCSB




Ricagno S., Jonsson S., Richards N. and Lindqvist Y.(2003) Formyl-CoA transferase encloses the CoA binding site at the interface of an interlocked dimer. EMBO J. 22, 3210-3219.
Decameric Fructose 6-phosphate aldolase (MipB) 1L6W at RCSB
Thorell, S., Schürmann, M., Sprenger, G.A. and Schneider, G. (2002) Crystal structure of decameric fructose-6-phosphate aldolase from Escherichia coli reveals inter-subunit helix swapping as the structural basis for assembly differences in the transaldolase family. Journal Mol. Biol. 319, 161-171
Gluconate Kinase  1KNQ, 1KO1, 1KO4 1KOF, 1KO5, 1KO8, at RCSB

 

Kraft, L., Sprenger, GA., Lindqvist, Y. (2002) Conformational Changes During the Catalytic Cycle of Gluconate Kinase as Revealed by X-ray Crystallography.  Journal Mol. Biol, 318. 1057-1069

Carbohydrate recognition domain of p58/ERGIC-53 1GV9, 1R1Z at RCSB
Velloso LM, Svensson K, Schneider G, Pettersson RF, Lindqvist Y.(2002)  Crystal structure of the carbohydrate recognition domain of p58/ERGIC-53, a protein involved in glycoprotein export from the endoplasmic reticulum. Journal Biol Chem. 277, 15979-15984.
Mammalian Thioredoxin Reductase 1H6V3EAN, 3EAO  at RCSB
Sandalova T, Zhong L, Lindqvist Y, Holmgren A, Schneider G (2001) Three-dimensional structure of a mammalian thioredoxin reductase: Implications for mechanism and evolution of a selenocysteine-dependent enzyme.  Proc. Natl. Acad. Sci. U S A ., 98, 9533-9538
NrdH 1H75 , 1R7H  at RCSB
Stehr M, Schneider G, Åslund F, Holmgren A, Lindqvist Y (2001) Structural basis for the thioredoxin-like activity profile of the glutaredoxin-like protein NrdH-redoxin from Escherichia coli. J Biol Chem. , 276 , 35836-35841
Dihydropyrimidine Dehydrogenase 1H7X, 1H7W, 1GT8, 1GTE, 1GTH at RCSB
Dobritzsch,D, Schneider,G, Schnackerz,KD and Lindqvist,Y* (2001) Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil. 
 EMBO J. , 20 , 650-660.
Class II mouse Alcohol Dehydrogenase 1E3E, 1E3I1E3L at RCSB
Svensson, S., Höög, J.-O., Schneider, G. and Sandalova, T. (2000) Crystal structures of mouse class II alcohol dehydrogenase reveal determinants of substrate specificity and catalytic efficiency. 
J. Mol. Biol., 302, 441-453
Saccharopine Reductase 1E5L, 1E5Q, 1FF9 at RCSB
 Johansson, E., Steffens, J.J., Lindqvist,Y. and Schneider,G. (2000) Crystal Structure of Saccharopine Reductase from Magnaporthe grisea, an Enzyme of the alpha-Aminoadipate Pathway of Lysine Biosynthesis. Structure, 8, 1037-1047.
Purple Acid Phosphatase 1QHW at RCSB
Lindqvist,Y, Johansson,E., Kaija,H., Vihko,P. & Schneider,G. (1999) Three-dimensional Structure of a Mammalian Purple Acid Phosphatase at 2.2Å Resolution with a mu-(Hydr)oxo Bridged Di-iron Center.
J. Mol. Biol., 291, 135-147
Human Pro-Matrix Metalloproteinase-2 (Gelatinase A) 1CK7 at RCSB
Morgunova,E., Tuuttila,A., Bergmann,U., Isupov,M., Lindqvist,Y., Schneider,G., & Tryggvason,K. (1999) Structure of Human Pro-Matrix Metalloproteinases-2: Activation Mechanism Revealed. Science, 284, 1667-1670 
7,8-Diaminopelargonic Acid Synthase 1QJ3, 1QJ5, 1MGV, 1MLY, 1MLZ at RCSB
Käck,H., Sandmark,J., Gibson,K., Schneider,G., & Lindqvist,Y. (1999) Crystal Structure of Diaminopelargonic Acid Synthase: Evolutionary Relationships between Pyridoxal-5’-phosphate-dependent Enzymes.
J. Mol. Biol. , 291 , 857-876 
Lumazine Synthase 1C2Y, 1C41at RCSB
Persson, K., Schneider, G., Jordan, D. B., Viitanen, P.V., and  Sandalova, T. (1999) Crystal structure analysis of a pentameric fungal and an icosahedral plant lumazine synthase reveals the structural basis for differences in assembly. Protein Sci., 8 , 2355-2365
Pyruvate Decarboxylase 1ZPD, 1QPB, 1OVM at RCSB
Dobritzsch, D., König, S., Schneider, G. and Lu, G. (1998) High resolution structure of pyruvate decarboxylase from Zymomonas mobilis: implications for substrate activation in pyruvate decarboxylases. J. Biol. Chem., 273, 20196-20204
Tissue Inhibitor of Matrix Metalloproteinases-2 1BR9 at RCSB
Tuuttila,A., Morgunova,E., Bergmann,U., Lindqvist,Y., Maskos,K., Fernandez-Catalan,C., Bode,W., Tryggvason,K. & Schneider,G. (1998) Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1Å resolution.  J. Mol. Biol. , 284 , 1133-1140 
MHC class1 1BII 1N59, 1N5A , 1ZHB, 1S7Q, 1S7S, 1S7T, 1S7U, 1S7X, 1S7W, 1S7R, 1S7V, 2F74   at RCSB
Achour,A., Persson,K., Harris,R.A., Sundbäck,J., Sentman,C.L., Lindqvist,Y., Schneider,G. & Kärre,K. (1998) The crystal structure of H-2Dd MHC class I complexed with the HIV derived peptide P18-I10 at 2.4Å resolution: implications for T-cell and Natural Killer cell recognition. Immunity, 9, 199-208
Phenol Hydroxylase 1FOH at RCSB
Enroth,C., Neujahr,H., Schneider,G. and Lindqvist,Y. (1998) The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis. Structure, 6, 605-617 
Ketoacyl ACP-synthase II 1E5M, 1B3N, 1KAS at RCSB
Huang,W., Jia,J., Edwards,P., Dehesh,K., Schneider,G. and Lindqvist,Y. (1998) Crystal structure of beta-keto-acyl carier protein synthase II from E. coli reveals the molecular architecture of condensing enzymes. EMBO J., 17 , 1183-1191 
Nitrile hydratase 1AHJ at RCSB
Huang,W., Jia,J., Cummings,J., Nelson,M., Schneider,G. and Lindqvist,Y. (1997) Crystal structure of nitrile hydratase reveals a novel iron centre in a novel fold. Structure, 5, 691-699
Trihydroxynaphthalene reductase 1YBV at RCSB
Andersson,A., Jordan,D., Schneider,G. and Lindqvist, Y. (1996) Crystal structure of the ternary complex of 1,3,8-trihydroxynaphtalene reductase from Magnaporthe grisea  with NADPH and an active site inhibitor.  Structure, 4, 1161-1170 
Desaturase 1AFR, 1OQ4, 1OQ7, 1OQ9, 1OQB, 2J2F, 2UW1 at RCSB
Lindqvist,Y., Huang,W., Schneider,G. and Shanklin,J. (1996) Crystal structure of delta9 stearoyl-acyl carrier protein desaturase from Castor seed and its relationship to other diiron proteins.  EMBO J., 15 , 4081-4092 
Transaldolase 1I2Q, 1I2R, 1I2N, 1I2O, 1I2P1FO5, 1UCW, 1ONR, 3CWN  at RCSB
Jia,J., Huang,W., Schörken,U., Sahm,H., Sprenger,G.A., Lindqvist,Y. and Schneider,G. (1996) Crystal structure of transaldolase B from Escherichia coli  suggests a circular permutation of the alpha/beta barrel within the class I aldolase family. Structure, 4, 715-724
Dethiobiotin Synthetase 1BYI, 1DTS, 1BS1, 1DAM , 1DAE, 1DAF1DAG, 1DAH, 1DAI, 1DAD, 1DAK, 1A82 at RCSB
Huang,W.,. Lindqvist Y., Schneider, G., Gibson, K., Flint,D. & Lorimer,G. (1994) Crystal Structure of an ATP-dependent carboxylase, dethiobiotin synthetase, at 1.65 Å  resolution. Structure, 2, 407-414 
Nitrate Reductase 1CNE, 1CNF, 2CND at RCSB
Lu, G.G., Campbell,W.H., Schneider,G. & Lindqvist,Y. (1994) Crystal structure of the FAD-containing fragment of corn nitrate reductase at 2.5 Å  resolution: relationship to other flavoprotein reductases. Structure, 2 , 809-821
Scytalone Dehydratase 7STD, 6STD, 5STD4STD, 1STD, at RCSB
Lundqvist,T., Rice,J., Pierce,J. and Lindqvist Y. (1994) Crystal structure of scytalone dehydratase -a disease determinant of the rice pathogen, Magnaporthe grisea. Structure, 2, 937-944
Acid Phosphatase 1RPT, 1RPA   at RCSB
Schneider,G., Lindqvist,Y. and Vihko,P. (1993) Three-Dimensional Structure of Rat Acid Phosphatase
EMBO J., 12, 2609-2615
Transketolase 1GPU 1AYO , 1NGS, 1TRK, 1TKB, 1TKC, 1TKA, 1TKB, 1R9J  at RCSB
Lindqvist,Y., Schneider,G., Ermler,U. & Sundström,M. (1992) Three-dimensional Structure of Transketolase from baker´s yeast, a Thiamine Diphosphate dependent enzyme. EMBO J., 11, 2373-2379
Rubisco 1RBA, 1RUS, 2RUS, 5RUB, 9RUB at RCSB
Schneider,G., Lindqvist,Y., Brändén,C.-I. and Lorimer,G. (1986) Three-dimensional Structure of Ribulose-1,5-bisphosphate Carboxylase/Oxygenase from Rhodospirillum rubrum  at 2.9Å  resolution.
EMBO J., 5, 3409-3415
Glycolate Oxidase 1AL7, 1AL8, 1GYL, 1GOX at RCSB
Lindqvist,Y. and Brändén,C.-I. (1985) Structure of Glycolate Oxidase from Spinach.
Proc. Natl. Acad. Sci. U.S.A., 82 , 6855-6859